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Article

Role for Drs2p, a P-type ATPase and potential aminophospholipid translocase, in yeast late Golgi function.

The Journal of cell biology - 13 Dec 1999

Chen C Y, Ingram M F, Rosal P H, Graham T R

Abstract excerpt

ADP-ribosylation factor appears to regulate the budding of both COPI and clathrin-coated transport vesicles from Golgi membranes. An arf1Delta synthetic lethal screen identified SWA3/DRS2, which encodes an integral membrane P-type ATPase and potential aminophospholipid translocase (or flippase). The drs2 null allele is also synthetically lethal with clathrin heavy chain (chc1) temperature-sensitive alleles, but...

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Identifiers

PMID: 10601336
DOI: 10.1083/jcb.147.6.1223
PMCID: PMC2168089

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