Article
Phosphoinositide-mediated clathrin adaptor progression at the trans-Golgi network.
Nature cell biology - 19 Feb 2012
Daboussi Lydia, Costaguta Giancarlo, Payne Gregory S
Abstract excerpt
Clathrin-coated vesicles mediate endocytosis and transport between the trans-Golgi network (TGN) and endosomes in eukaryotic cells. Clathrin adaptors play central roles in coat assembly, interacting with clathrin, cargo and membranes. Two main types of clathrin adaptor act in TGN-endosome traffic: GGA proteins and the AP-1 complex. Here we characterize the relationship between GGA proteins, AP-1 and other TGN...
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