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Article

Phosphatidylserine translocation at the yeast trans-Golgi network regulates protein sorting into exocytic vesicles.

Molecular biology of the cell - 15 Dec 2015

Hankins Hannah M, Sere Yves Y, Diab Nicholas S, Menon Anant K, Graham Todd R

Abstract excerpt

Sorting of plasma membrane proteins into exocytic vesicles at the yeast trans-Golgi network (TGN) is believed to be mediated by their coalescence with specific lipids, but how these membrane-remodeling events are regulated is poorly understood. Here we show that the ATP-dependent phospholipid flippase Drs2 is required for efficient segregation of cargo into exocytic vesicles. The plasma membrane proteins Pma1 and...

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Source

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Identifiers

PMID: 26466678
DOI: 10.1091/mbc.E15-07-0487
PMCID: PMC4678023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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