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Article

Roles for the Drs2p-Cdc50p complex in protein transport and phosphatidylserine asymmetry of the yeast plasma membrane.

Traffic (Copenhagen, Denmark) - 1 Nov 2006

Chen Sophie, Wang Jiyi, Muthusamy Baby-Periyanayaki, Liu Ke, Zare Sara, Andersen Raymond J, Graham Todd R

Abstract excerpt

Drs2p, a P-type adenosine triphosphatase required for a phosphatidylserine (PS) flippase activity in the yeast trans Golgi network (TGN), was first implicated in protein trafficking by a screen for mutations synthetically lethal with arf1 (swa). Here, we show that SWA4 is allelic to CDC50, encoding a membrane protein previously shown to chaperone Drs2p from the endoplasmic reticulum to the Golgi complex. We find...

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PMID: 16956384
DOI: 10.1111/j.1600-0854.2006.00485.x

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Roles for the Drs2p-Cdc50p complex in protein transport and phosphatidylserine asymmetry of the yeast plasma membrane.PMID 16956384Read ↗

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