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Article

Drs2p-dependent formation of exocytic clathrin-coated vesicles in vivo.

Current biology : CB - 17 Sept 2002

Gall Walter E, Geething Nathan C, Hua Zhaolin, Ingram Michael F, Liu Ke, Chen Sophie I, Graham Todd R

Abstract excerpt

The small GTP binding protein ARF has been implicated in budding clathrin-coated vesicles (CCVs) from Golgi and endosomal membranes. An arf1 synthetic lethal screen identified DRS2/SWA3 along with a clathrin heavy-chain conditional allele (chc1-5/swa5-1) and SWA2, encoding the yeast auxilin-like protein involved in uncoating CCVs. Drs2p/Swa3p is a P-type ATPase and a potential aminophospholipid translocase that...

Topics

Adaptor Protein Complex 1
Calcium-Transporting ATPases
Carrier Proteins
Clathrin Heavy Chains
Clathrin-Coated Vesicles
Exocytosis
Gene Deletion
Genes, Fungal
Microscopy, Electron
Mutation
Phosphoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Vesicular Transport Proteins

Source

Identifiers

PMID: 12372257
DOI: 10.1016/s0960-9822(02)01148-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12372257-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Drs2p-dependent formation of exocytic clathrin-coated vesicles in vivo.PMID 12372257Read ↗

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