Article
Vps10p transport from the trans-Golgi network to the endosome is mediated by clathrin-coated vesicles.
Molecular biology of the cell - 1 Feb 2001
Deloche O, Yeung B G, Payne G S, Schekman R
Abstract excerpt
A native immunoisolation procedure has been used to investigate the role of clathrin-coated vesicles (CCVs) in the transport of vacuolar proteins between the trans-Golgi network (TGN) and the prevacuolar/endosome compartments in the yeast Saccharomyces cerevisiae. We find that Apl2p, one large subunit of the adaptor protein-1 complex, and Vps10p, the carboxypeptidase Y vacuolar protein receptor, are associated...
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