Article
Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach.
Human genetics - 1 Jul 2008
Rhodes Benjamin, Morris David L, Subrahmanyan Lakshman, Aubin Cristin, de Leon Carlos F Mendes, Kelly Jeremiah F, Evans Dennis A, Whittaker John C, Oksenberg Jorge R, De Jager Philip L, Vyse Tim J
Abstract excerpt
Basal levels of C-reactive protein (CRP) have been associated with disease, particularly future cardiovascular events. Twin studies estimate 50% CRP heritability, so the identification of genetic variants influencing CRP expression is important. Existing studies in populations of European ancestry have identified numerous cis-acting variants but leave significant ambiguity over the identity of the key functional...
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