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Article

A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A and alphaviruses fails to cleave Sindbis virus glycoprotein PE2.

Journal of virology - 1 May 1991

Watson D G, Moehring J M, Moehring T J

Abstract excerpt

RPE.40, a mutant CHO-K1 strain selected for resistance to Pseudomonas exotoxin A, is defective in the production of infectious alphaviruses, although viruses are taken in and processed normally (J. M. Moehring and T. J. Moehring, Infect. Immun. 41:998-1009, 1983). To determine the cause of this defect, the synthesis of Sindbis virus proteins was examined. RPE.40 cells produced and glycosylated structural...

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Identifiers

PMID: 1850015
DOI: 10.1128/JVI.65.5.2332-2339.1991
PMCID: PMC240584

Genes

RPE

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Source receipt: pubmed, retrieved 7 Sept 2026.

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