Article
A mutant CHO-K1 strain with resistance to Pseudomonas exotoxin A and alphaviruses fails to cleave Sindbis virus glycoprotein PE2.
Journal of virology - 1 May 1991
Watson D G, Moehring J M, Moehring T J
Abstract excerpt
RPE.40, a mutant CHO-K1 strain selected for resistance to Pseudomonas exotoxin A, is defective in the production of infectious alphaviruses, although viruses are taken in and processed normally (J. M. Moehring and T. J. Moehring, Infect. Immun. 41:998-1009, 1983). To determine the cause of this d...
Topics
- ADP Ribose Transferases
- Alphavirus
- Animals
- Bacterial Toxins
- Blotting, Western
- Cell Line
- Cricetinae
- Drug Resistance
- Electrophoresis, Polyacrylamide Gel
- Exotoxins
- Female
- Mutation
- Ovary
- Protein Precursors
- Sindbis Virus
- Trypsin
- Viral Envelope Proteins
- Virulence Factors