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Article

Linkage of an alphavirus host-range restriction to the carbohydrate-processing phenotypes of the host cell.

The Journal of general virology - 1 Jan 2000

Boehme K W, Williams J C, Johnston R E, Heidner H W

Abstract excerpt

The Sindbis virus mutant NE2G216 retains PE2 in place of E2 in its virion structure. NE2G216 is a host-range mutant that replicates with near-normal kinetics in vertebrate cells, but displays severely restricted growth in cultured mosquito cells (C6/36) due to defects in the virus maturation process. In this study we tested the hypothesis that the host-range phenotype of NE2G216 was linked to the differences in...

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PMID: 10640554
DOI: 10.1099/0022-1317-81-1-161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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