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Article

Interactions among genetic variants from contractile pathway of vascular smooth muscle cell in essential hypertension susceptibility of Chinese Han population.

Pharmacogenetics and genomics - 1 Jun 2008

Zhao Qi, Wang Laiyuan, Yang Wei, Chen Shufeng, Huang Jianfeng, Fan Zhongjie, Li Hongfan, Lu Xiangfeng, Gu Dongfeng

Abstract excerpt

BACKGROUND AND OBJECTIVE: Recent study supports the hypothesis that the abnormalities of vascular smooth muscle cell (VSMC) that alter the intrinsic contractile state of the cell can directly cause abnormal vascular tone and disorders of blood pressure regulation, including hypertension. This study aimed to explore the individual and interactive effects of five genes from the contractile pathway of VSMC (KCNMB1,...

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Share to Calcium-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle Contraction

Share to Muscle, Smooth, Vascular

Share to Myosin-Light-Chain Kinase

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Share to rho-Associated Kinases

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Source

Identifiers

PMID: 18496125
DOI: 10.1097/FPC.0b013e3282f97fb2

Genes

RGS2
MYLK
ROCK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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