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Article

Haplotype-based association of regulator of G-protein signaling 5 gene polymorphisms with essential hypertension and metabolic parameters in Chinese.

Clinical chemistry and laboratory medicine - 1 Jan 2009

Xiao Bing, Zhang Yi, Niu Wen-quan, Gao Pin-jing, Zhu Ding-liang

Abstract excerpt

BACKGROUND: A recent genome-wide linkage study mapped blood pressure (BP)-related loci on human chromosome 1q and identified the regulator of G-protein signaling 5 (RGS5) as a candidate for regulation of BP. Thus, we assessed the relationship between RGS5 genetic polymorphisms and essential hypertension (EH) in Chinese. METHODS: A total of 906 patients with EH and 894 age- and gender-matched normotensive (NT)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19863299
DOI: 10.1515/CCLM.2009.344

Genes

RGS5

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