Article
Genes involved in vasoconstriction and vasodilation system affect salt-sensitive hypertension.
PloS one - 9 May 2011
Citterio Lorena, Simonini Marco, Zagato Laura, Salvi Erika, Delli Carpini Simona, Lanzani Chiara, Messaggio Elisabetta, Casamassima Nunzia, Frau Francesca, D'Avila Francesca, Cusi Daniele, Barlassina Cristina, Manunta Paolo
Abstract excerpt
The importance of excess salt intake in the pathogenesis of hypertension is widely recognized. Blood pressure is controlled primarily by salt and water balance because of the infinite gain property of the kidney to rapidly eliminate excess fluid and salt. Up to fifty percent of patients with essential hypertension are salt-sensitive, as manifested by a rise in blood pressure with salt loading. We conducted a...
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