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Detection of genetic variations of regulator of G-protein signaling 2 in hypertensives by sequencing.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Apr 2011

Ju-hong Zhang, Nan-fang Li, Zhi-tao Yan, Xiao-guang Yao, Hong-mei Wang, De-lian Zhang, Xin-ling Wang

Abstract excerpt

OBJECTIVE: To investigate the new genetic variations of regulator of G-protein signalling 2 (RGS2) gene in Kazakh hypertensives. METHODS: Totally 94 Kazakh patients with essential hypertension were enrolled and genomic DNA was extracted from their peripheral blood leukocytes. All the exon regions and their flanking sequences of RGS2 were directly sequenced. RESULTS: We identified 13 variants including 5 common-...

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PMID: 21529451
DOI: 10.3881/j.issn.1000-503X.2011.02.020

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RGS2

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