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Article

Association of genetic variations of regulator of G-protein signaling 2 with hypertension in the general Xinjiang Kazakh population.

Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2010

Li Nan-Fang, Zhang Ju-Hong, Yang Jin, Zhou Ling, Luo Wen-Li, Guo Yan-Ying, Yao Xiao-Guang, Wang Hong-Mei, Chang Jian-Hang

Abstract excerpt

Mice deficiency in regulator of G-protein signaling 2(RGS2) showed an evident hypertension phenotype. Here, we studied associations of genetic variations of RGS2 with essential hypertension in the Kazakh population. Two identified nonsynonymous mutations (K18N, Y178C) were not specific for hypertension. A significant association was observed between 1891-1892 TC insertion/deletion with hypertension in men (OR =...

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Identifiers

PMID: 20662725
DOI: 10.3109/10641960903265253

Genes

RGS2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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