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Article

Graves' disease in Brazilian children and adults: lack of genetic association with CTLA-4 +49A>G polymorphism.

Hormone research - 1 Jan 2008

Namo Cury Adriano, Longui Carlos Alberto, Kochi Cristiane, Calliari Luiz Eduardo, Scalissi Nilza, Salles João Eduardo, Neves Rocha Mylene, Barbosa de Melo Mônica, Rezende Melo Murilo, Monte Osmar

Abstract excerpt

BACKGROUND/AIM: In several populations, major histocompatibility complex and CTLA-4 (cytotoxic T lymphocyte antigen-4) gene polymorphisms are related to adult subjects with Graves' disease (GD). Our aim was to study the association of +49A>G polymorphism of the CTLA-4 gene in Brazilian children and adults with GD and its correlation with clinical and laboratory markers of disease severity. METHODS: CTLA-4 +49A>G...

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PMID: 18493148
DOI: 10.1159/000129676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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