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Article

CTLA4 polymorphisms and ophthalmopathy in Graves' disease patients: association study and meta-analysis.

Human immunology - 1 Aug 2006

Han Shizhong, Zhang Suhua, Zhang Wenyu, Li Rong, Li Yao, Wang Zhentian, Xie Yi, Mao Yumin

Abstract excerpt

Studies in the past have clearly established that cytotoxic T-lymphocyte antigen-4 (CTLA4) is a susceptible gene for Graves' disease (GD). However, association studies between the CTLA4 exon-1 +49A/G polymorphism and the risk of developing Graves' ophthalmopathy (GO) in GD patients have revealed conflicting results. In this study, associations of two CTLA4 polymorphisms (+49A/G and CT60) with GD risk and GO...

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Source

Identifiers

PMID: 16916658
DOI: 10.1016/j.humimm.2006.05.003

Genes

CTLA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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CTLA4 polymorphisms and ophthalmopathy in Graves' disease patients: association study and meta-analysis.PMID 16916658Read ↗

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