Mutational analysis of antigen receptor regulation of B lymphocyte growth. Evidence for involvement of the phosphoinositide signaling pathway.

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Article

Mutational analysis of antigen receptor regulation of B lymphocyte growth. Evidence for involvement of the phosphoinositide signaling pathway.

The Journal of biological chemistry - 25 Mar 1991

Page D M, Gold M R, Fahey K A, Matsuuchi L, DeFranco A L

Abstract excerpt

Stimulation of the antigen receptor of WEHI-231 B lymphoma cells with anti-receptor antibodies (anti-IgM) induces irreversible growth arrest. Anti-IgM stimulates two kinds of transmembrane signaling events, phosphorylation of proteins on tyrosyl residues and breakdown of inositol phospholipids, w...

Topics

Animals
B-Lymphocytes
Calcium
Cell Division
Electrophoresis, Polyacrylamide Gel
GTP-Binding Proteins
Glycosylation
Immunoglobulin M
Ionomycin
Mice
Mutation
Phorbol Esters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphatidylinositols

Phosphorylation

Precipitin Tests

Receptors, Antigen

Second Messenger Systems

Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 1848555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1848555-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutational analysis of antigen receptor regulation of B lymphocyte growth. Evidence for involvement of the phosphoinositide signaling pathway.PMID 1848555Read ↗

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