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Article

Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.

PloS one - 18 Sept 2009

Li Ming D, Mangold Jamie E, Seneviratne Chamindi, Chen Guo-Bo, Ma Jennie Z, Lou Xiang-Yang, Payne Thomas J

Abstract excerpt

Previous studies have demonstrated that the gamma-aminobutyric acid type B (GABA(B)) receptor plays an essential role in modulating neurotransmitter release and regulating the activity of ion channels and adenyl cyclase. However, whether the naturally occurring polymorphisms in the two GABA(B) re...

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Source

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Identifiers

PMID: 19763258
DOI: 10.1371/journal.pone.0007055
PMCID: PMC2739294

Genes

GABBR2
GABBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19763258-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.PMID 19763258Read ↗

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Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.Semantic proximity Read ↗

Gene-based analysis suggests association of the nicotinic acetylcholine receptor beta1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence.Semantic proximity Read ↗

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