Article
HLA-DR2 and white matter lesion distribution in MS.
Journal of neuroimaging : official journal of the American Society of Neuroimaging - 1 Jul 2008
Sepulcre Jorge, Masdeu Joseph C, Palacios Ricardo, Goñi Joaquín, Moreno Beatriz, Tainta Mikel, Bejarano Bartolomé, Villoslada Pablo
Abstract excerpt
Human leukocyte antigen DR2 (HLA-DR2) is a well-established genetic risk factor for multiple sclerosis (MS). However, it is still unknown whether this factor is associated with a specific disease phenotype, and in particular, to a regional distribution of white matter (WM) lesion phenotype on magnetic resonance imaging (MRI). On a voxel-by-voxel basis, we analyzed the T1 and T2 MRI-derived lesion maps of 50...
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