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Article

Down‐regulation of claudin‐2 in breast carcinomas is associated with advanced disease

12 May 2008

Abstract excerpt

AIMS: Claudin 2 (CLDN2) is a family of integral membrane tight junctions. The aim was to determine the influence of CLDN2 expression on tumour behaviour and its role in breast carcinogenesis. METHOD AND RESULTS: Thirty-seven invasive breast carcinomas and corresponding normal breast tissues were examined for CLDN2 protein and mRNA expression using Western blotting and semiquantitative reverse...

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PMID: 18479414
DOI: 10.1111/j.1365-2559.2008.03052.x

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