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Article

Claudin 1 in Breast Cancer: New Insights

27 Nov 2015

Abstract excerpt

Claudin 1 is a small transmembrane protein responsible for maintaining the barrier function that exists between epithelial cells. A tight junction protein that regulates the paracellular transport of small ions across adjacent cells, claudin 1 maintains cellular polarity and plays a major role in cell-cell communication and epithelial cell homeostasis. Long considered to be a putative tumor suppressor in human...

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PMID: 26633531
DOI: 10.3390/jcm4121952

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