Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A CLDN1-negative phenotype predicts poor prognosis in triple-negative breast cancer.

PloS one - 1 Jan 2014

Ma Fei, Ding Xiaoyan, Fan Ying, Ying Jianming, Zheng Shan, Lu Ning, Xu Binghe

Abstract excerpt

INTRODUCTION: Triple-negative breast cancer (TNBC) is a heterogeneous disease with no definitive prognostic markers. As a major component of tight junctions, claudins (CLDNs) presumably play an important role in carcinogenesis and progression of breast cancer. This study was aimed at determining the relationship between the expression of CLDNs and the clinical outcomes of TNBCs. MATERIALS AND METHODS: The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Ductal
Share to Carcinoma, Lobular
Share to Claudin-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Claudins

Share to Lymph Nodes

Share to Lymphatic Metastasis

Share to Neoplasm Grading

Share to Triple Negative Breast Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25393310
DOI: 10.1371/journal.pone.0112765
PMCID: PMC4231092

Genes

CLDN1
CLDN4
CLDN2
CLDN7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A CLDN1-negative phenotype predicts poor prognosis in triple-negative breast cancer.PMID 25393310Read ↗

Decreased expression of claudin-1 correlates with recurrence status in breast cancerSemantic proximity Read ↗

Claudin-Low Breast Cancer; Clinical & Pathological Characteristics.Semantic proximity Read ↗

Claudin-1, A Double-Edged Sword in CancerSemantic proximity Read ↗

Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterizationSemantic proximity Read ↗

[Is there a claudin-low phenotype of breast cancer?]Semantic proximity Read ↗

Targeting claudin-4 enhances chemosensitivity of triple negative breast cancerSemantic proximity Read ↗

Overexpression of CCNE1 confers a poorer prognosis in triple-negative breast cancer identified by bioinformatic analysisSemantic proximity Read ↗

Overexpression of CCNE1 confers a poorer prognostic in triple negative breast cancer identified by bioinformatic analysisSemantic proximity Read ↗

VDAC1 Conversely Correlates with Cytc Expression and Predicts Poor Prognosis in Human Breast Cancer PatientsSemantic proximity Read ↗

Expression of long non‐coding RNA ENSG 00000226738 (Lnc KLHDC 7B) is enriched in the immunomodulatory triple‐negative breast cancer subtype and its alteration promotes cell migration, invasion, and resistance to cell deathSemantic proximity Read ↗

Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer.Semantic proximity Read ↗

Prevalence and clinical significance of Claudin-3 expression in cancer: a tissue microarray study on 14,966 tumor samplesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.