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Dysregulated expression of claudins in cancer (Review)

7 Jul 2021

Abstract excerpt

Claudins are adhesion molecules located at the tight junctions between epithelial cells. A series of studies have now reported aberrant expression of claudin proteins in the context of neoplastic transformation, suggesting its role in tumorigenesis. However, the precise mechanisms are still not well understood. Studies on expression alterations of claudins have revealed a range of outcomes that reflect the...

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PMID: 34386063
DOI: 10.3892/ol.2021.12902

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