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Article

The claudin gene family: expression in normal and neoplastic tissues

12 Jul 2006

Abstract excerpt

BACKGROUND: The claudin (CLDN) genes encode a family of proteins important in tight junction formation and function. Recently, it has become apparent that CLDN gene expression is frequently altered in several human cancers. However, the exact patterns of CLDN expression in various cancers is unknown, as only a limited number of CLDN genes have been investigated in a few tumors. METHODS: We identified all the...

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PMID: 16836752
DOI: 10.1186/1471-2407-6-186

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