Article
Isocitrate dehydrogenase kinase/phosphatase: aceK alleles that express kinase but not phosphatase activity.
Journal of bacteriology - 1 Mar 1991
Ikeda T, LaPorte D C
Abstract excerpt
For Escherichia coli, growth on acetate requires the induction of the enzymes of the glyoxylate bypass, isocitrate lyase and malate synthase. The branch point between the glyoxylate bypass and the Krebs cycle is controlled by phosphorylation of isocitrate dehydrogenase (IDH), inhibiting that enzyme's activity and thus forcing isocitrate through the bypass. This phosphorylation cycle is catalyzed by a bifunctional...
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