Article
Isocitrate dehydrogenase kinase/phosphatase: identification of mutations which selectively inhibit phosphatase activity.
Journal of bacteriology - 1 Feb 1992
Ikeda T P, Houtz E, LaPorte D C
Abstract excerpt
Mutations in aceK, the gene encoding isocitrate dehydrogenase kinase/phosphatase, which selectively inhibit phosphatase activity have been isolated. These mutations yield amino acid substitutions within a 113-residue region of this 578-residue protein. These mutations may define a regulatory domain of this protein.
Topics
- DNA Mutational Analysis
- Escherichia coli
- Mutation
- Phosphoprotein Phosphatases
- Protein Kinases
- Protein Serine-Threonine Kinases
- Transformation, Bacterial