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Article

Acetyl-phosphate is a critical determinant of lysine acetylation in E. coli.

Molecular cell - 25 Jul 2013

Weinert Brian T, Iesmantavicius Vytautas, Wagner Sebastian A, Schölz Christian, Gummesson Bertil, Beli Petra, Nyström Thomas, Choudhary Chunaram

Abstract excerpt

Lysine acetylation is a frequently occurring posttranslational modification in bacteria; however, little is known about its origin and regulation. Using the model bacterium Escherichia coli (E. coli), we found that most acetylation occurred at a low level and accumulated in growth-arrested cells in a manner that depended on the formation of acetyl-phosphate (AcP) through glycolysis. Mutant cells unable to produce...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23830618
DOI: 10.1016/j.molcel.2013.06.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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