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Article

Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation.

Genome research - 1 Jan 2009

Milani Lili, Lundmark Anders, Nordlund Jessica, Kiialainen Anna, Flaegstad Trond, Jonmundsson Gudmundur, Kanerva Jukka, Schmiegelow Kjeld, Gunderson Kevin L, Lönnerholm Gudmar, Syvänen Ann-Christine

Abstract excerpt

To identify genes that are regulated by cis-acting functional elements in acute lymphoblastic leukemia (ALL) we determined the allele-specific expression (ASE) levels of 2, 529 genes by genotyping a genome-wide panel of single nucleotide polymorphisms in RNA and DNA from bone marrow and blood samples of 197 children with ALL. Using a reproducible, quantitative genotyping method and stringent criteria for scoring...

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Identifiers

PMID: 18997001
DOI: 10.1101/gr.083931.108
PMCID: PMC2612957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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