Article
Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen.
Journal of virology - 1 Aug 1990
Ulug E T, Hawkins P T, Hanley M R, Courtneidge S A
Abstract excerpt
Associated with the middle T antigen of polyomavirus is a novel phosphatidylinositol (PtdIns) kinase activity which phosphorylates PtdIns at the D-3 position of the inositol ring. We have undertaken an analysis of myo-[3H]inositol-containing compounds in a panel of NIH 3T3 cell lines stably transfected with transforming and nontransforming middle T antigen mutants. All cell lines from which PtdIns 3-kinase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
