Article
Abl kinase but not PI3-kinase links to the cytoskeletal defects in Bcr-Abl transformed cells.
Experimental hematology - 1 Jan 2000
Gaston I, Stenberg P E, Bhat A, Druker B J
Abstract excerpt
OBJECTIVE: The purpose of this study was to investigate the contribution of Abl kinase and phosphatidylinositol 3-kinase (PI3-kinase) to the altered adhesive properties and cytoskeletal defects in a Bcr-Abl transformed fibroblast cell model. MATERIALS ANID METHODS: Two fibroblast cell lines stably transfected with Bcr-Abl were compared to their parental counterparts for alterations in their adhesive properties in...
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