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Article

Role of the <i>WWOX</i> gene, encompassing fragile region <i>FRA16D</i>, in suppression of pancreatic carcinoma cells

2 May 2008

Abstract excerpt

The WW-domain-containing oxidoreductase (WWOX) gene spans the common chromosomal fragile site FRA16D (16q23.2) and is believed to be a tumor suppressor in various human malignancies. We have previously shown frequent down-modulation of Wwox expression in pancreatic carcinoma (PC); however, biological function of Wwox in pancreatic duct carcinogenesis remains unknown. In PANC-1 (Wwox-negative) PC-derived cells,...

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Identifiers

PMID: 18460020
DOI: 10.1111/j.1349-7006.2008.00841.x

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Role of the <i>WWOX</i> gene, encompassing fragile region <i>FRA16D</i>, in suppression of pancreatic carcinoma cellsPMID 18460020Read ↗

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