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Article

Abnormalities of tumor suppressor gene p16 in pancreatic carcinoma: immunohistochemical and genetic findings compared with clinicopathological parameters.

Journal of gastroenterology - 1 Jan 2003

Ohtsubo Koushiro, Watanabe Hiroyuki, Yamaguchi Yasushi, Hu Yu-Xin, Motoo Yoshiharu, Okai Takashi, Sawabu Norio

Abstract excerpt

BACKGROUND: Abnormalities of the tumor suppressor gene p16 have been reported in a variety of human tumors but are rare in pancreatic carcinoma except for cancer cell lines and xenografts. Their clinicopathological significance remains unknown. The purpose of this study was to examine immunohistochemical and genetic alterations of p16 in primary pancreatic carcinoma tissues and to investigate the relation between...

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Identifiers

PMID: 12898359
DOI: 10.1007/s00535-003-1119-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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