Mutants of feline immunodeficiency virus resistant to 3'-azido-3'-deoxythymidine.

doi:10.1128/JVI.65.1.308-312.1991

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Article

Mutants of feline immunodeficiency virus resistant to 3'-azido-3'-deoxythymidine.

Journal of virology - 1 Jan 1991

Remington K M, Chesebro B, Wehrly K, Pedersen N C, North T W

Abstract excerpt

We selected 3'-azido-3'-deoxythymidine (AZT)-resistant mutants of feline immunodeficiency virus (FIV) in a cat cell culture system. The characterization of one of these mutants was facilitated by the development of a focal immunoassay which could accurately measure FIV infectivity. This assay was...

Topics

Animals
Antiviral Agents
Cats
Cell Line
Drug Resistance, Microbial
Immunodeficiency Virus, Feline
Kinetics
Mutation
Zidovudine

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