Article
Mutants of feline immunodeficiency virus resistant to 3'-azido-3'-deoxythymidine.
Journal of virology - 1 Jan 1991
Remington K M, Chesebro B, Wehrly K, Pedersen N C, North T W
Abstract excerpt
We selected 3'-azido-3'-deoxythymidine (AZT)-resistant mutants of feline immunodeficiency virus (FIV) in a cat cell culture system. The characterization of one of these mutants was facilitated by the development of a focal immunoassay which could accurately measure FIV infectivity. This assay was used to quantitate the susceptibility of FIV to various inhibitors. The AZT-resistant mutant was found to be...
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