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Article

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

Diabetes - 1 Aug 2008

Dallaire Patrice, Bellmann Kerstin, Laplante Mathieu, Gélinas Stéphanie, Centeno-Baez Carolina, Penfornis Patrice, Peyot Marie-Line, Latour Martin G, Lamontagne Julien, Trujillo Maria E, Scherer Philipp E, Prentki Marc, Deshaies Yves, Marette André

Abstract excerpt

OBJECTIVE: Synthetic ligands for peroxisome proliferator-activated receptor-gamma (PPAR-gamma) improve insulin sensitivity in obesity, but it is still unclear whether inflammatory signals modulate their metabolic actions. In this study, we tested whether targeted disruption of inducible nitric ox...

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Identifiers

PMID: 18458147
DOI: 10.2337/db08-0540
PMCID: PMC2494686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18458147-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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