Article
PPAR gamma as a metabolic regulator: insights from genomics and pharmacology.
Expert reviews in molecular medicine - 25 Jan 2005
Savage David B
Abstract excerpt
Since its identification in the early 1990 s, peroxisome-proliferator-activated receptor gamma (PPAR gamma), a nuclear hormone receptor, has attracted tremendous scientific and clinical interest. The role of PPAR gamma in macronutrient metabolism has received particular attention, for three main reasons: first, it is the target of the thiazolidinediones (TZDs), a novel class of insulin sensitisers widely used to...
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