Article
Structural variation of the mouse natural killer gene complex.
Genes and immunity - 1 Dec 2010
Higuchi D A, Cahan P, Gao J, Ferris S T, Poursine-Laurent J, Graubert T A, Yokoyama W M
Abstract excerpt
The natural killer gene complex (NKC) on chromosome 6 contains clusters of genes that encode both activation and inhibitory receptors expressed on mouse natural killer (NK) cells. NKC genes, particularly belonging to the Nkrp1 and Ly49 gene families, display haplotype differences between different mouse strains and allelic polymorphisms of individual genes, as previously revealed by conventional analysis in a...
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