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Article

Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.

Metabolism: clinical and experimental - 1 May 2008

Staiger Harald, Machicao Fausto, Werner Roman, Guirguis Alke, Weisser Melanie, Stefan Norbert, Fritsche Andreas, Häring Hans-Ulrich

Abstract excerpt

Angiopoietin-like protein 4 (ANGPTL4) represents an adipokine with metabolic effects within adipose tissue, such as inhibition of lipoprotein lipase activity and stimulation of lipolysis. These effects were convincingly demonstrated in mice. Therefore, we asked whether genetic variation within the ANGPTL4 gene contributes to prediabetic phenotypes, such as dyslipidemia, insulin resistance, or beta-cell...

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Share to Angiopoietins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fatty Acids, Nonesterified

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Share to Intercellular Signaling Peptides and Proteins

Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 18442626
DOI: 10.1016/j.metabol.2007.12.007

Genes

ANGPTL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.PMID 18442626Read ↗

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No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes.Semantic proximity Read ↗

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Association between angiopoietin-like 6 (ANGPTL6) gene polymorphisms and metabolic syndrome-related phenotypes in the French MONICA Study.Semantic proximity Read ↗

Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.Semantic proximity Read ↗

Common genetic variants in fatty acid-binding protein-4 (FABP4) and clinical diabetes risk in the Women's Health Initiative Observational Study.Semantic proximity Read ↗

Association between rs2278426 (C/T) and rs892066 (C/G) variants of ANGPTL8 (betatrophin) and susceptibility to type2 diabetes mellitus.Semantic proximity Read ↗

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