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Article

Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.

Obesity (Silver Spring, Md.) - 1 May 2008

Qi Lu, Zhang Cuilin, Greenberg Andrew, Hu Frank B

Abstract excerpt

OBJECTIVE: The variations in perilipin gene (PLIN) were previously associated with obesity and insulin sensitivity. We examined whether PLIN variability was associated with diabetes risk and obesity status modified such associations. METHODS AND PROCEDURES: We conducted a nested case-control study of 431 incident cases of type 2 diabetes and 791 healthy control women from the Nurses' Health Study. Obesity was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18356850
DOI: 10.1038/oby.2008.26
PMCID: PMC3925667

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common variations in perilipin gene, central obesity, and risk of type 2 diabetes in US women.PMID 18356850Read ↗

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Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women.Semantic proximity Read ↗

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A functional variant in the exon 5 of PLIN1 reduces risk of central obesity by possible regulation of lipid storage.Semantic proximity Read ↗

Genetic variation at the perilipin locus is associated with changes in serum free fatty acids and abdominal fat following mild weight loss.Semantic proximity Read ↗

Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.Semantic proximity Read ↗

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Study of the impact of perilipin polymorphisms in a French population.Semantic proximity Read ↗

Polymorphisms in perilipin gene (PLIN) are not associated with obesity and weight variation in people with high risk of type 2 diabetes.Semantic proximity Read ↗

Perilipin polymorphism interacts with dietary carbohydrates to modulate anthropometric traits in hispanics of Caribbean origin.Semantic proximity Read ↗

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