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Article

Common genetic variants in fatty acid-binding protein-4 (FABP4) and clinical diabetes risk in the Women's Health Initiative Observational Study.

Obesity (Silver Spring, Md.) - 1 Sept 2010

Chan Kei-Hang K, Song Yiqing, Hsu Yi-Hsiang, You Nai-Chieh Y, F Tinker Lesley, Liu Simin

Abstract excerpt

Adipocypte fatty acid-binding protein-4 (FABP4/adipocyte P2) may play a central role in energy metabolism and inflammation. In animal models, defects of the aP2 gene (aP2(-/-)) partially protected against the development of obesity-related insulin resistance, dyslipidemia, and atherosclerosis. However, it is unclear whether common genetic variation in FABP4 gene contributes to risk of type 2 diabetes (T2D) or...

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C-Reactive Protein
E-Selectin
Fatty Acid-Binding Proteins
Inflammation Mediators
Intercellular Adhesion Molecule-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vascular Cell Adhesion Molecule-1

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Open in PubMed Open full text

Identifiers

PMID: 20111020
DOI: 10.1038/oby.2009.496
PMCID: PMC3192651

Genes

FABP4
TNF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Common genetic variants in fatty acid-binding protein-4 (FABP4) and clinical diabetes risk in the Women's Health Initiative Observational Study.PMID 20111020Read ↗

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