Article
Transgenic mice and squamous multistage skin carcinogenesis.
Cancer metastasis reviews - 1 Jun 1995
Brown K, Balmain A
Abstract excerpt
The use of animals models of human cancers has proved useful in the elucidation of molecular events which occur during tumour development. Mouse skin has been used as a model for human squamous cancer for a number of decades, and analysis of this model has identified a number of changes important for the evolution of malignancy. Transgenic mice offer a further avenue of advancement, allowing refinement of the...
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