Transgenic mice and squamous multistage skin carcinogenesis.

doi:10.1007/BF00665795

Back to search

Article

Transgenic mice and squamous multistage skin carcinogenesis.

Cancer metastasis reviews - 1 Jun 1995

Brown K, Balmain A

Abstract excerpt

The use of animals models of human cancers has proved useful in the elucidation of molecular events which occur during tumour development. Mouse skin has been used as a model for human squamous cancer for a number of decades, and analysis of this model has identified a number of changes important...

Topics

Animals
Carcinogens
Carcinoma, Squamous Cell
Growth Substances
Humans
Mice
Mice, Knockout
Mice, Transgenic
Oncogenes
Phenotype
Skin Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.