Article
Predominant Ashkenazi BRCA1/2 mutations in families with pancreatic cancer.
Genetic testing - 1 Jun 2008
Dagan Efrat
Abstract excerpt
The present study aimed to identify pancreatic cancer patients who harbor a mutation in BRCA1/2 genes within hereditary breast-ovarian cancer families. History of cancer in 1014 families that attended our breast-ovarian oncogenetic clinic was evaluated. Twenty-three families with pancreatic cancer were studied. In nine families wherein the probands themselves presented with pancreatic cancer, two (22%) carried a...
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