Article
Risk of pancreatic cancer in breast cancer families from the breast cancer family registry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2013
Mocci Evelina, Milne Roger L, Méndez-Villamil Elena Yuste, Hopper John L, John Esther M, Andrulis Irene L, Chung Wendy K, Daly Mary, Buys Saundra S, Malats Nuria, Goldgar David E
Abstract excerpt
BACKGROUND: Increased risk of pancreatic cancer has been reported in breast cancer families carrying BRCA1and BRCA2 mutations; however, pancreatic cancer risk in mutation-negative (BRCAX) families has not been explored to date. The aim of this study was to estimate pancreatic cancer risk in high-risk breast cancer families according to the BRCA mutation status. METHODS: A retrospective cohort analysis was applied...
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