Article
Family history of cancer and germline BRCA2 mutations in sporadic exocrine pancreatic cancer.
Gut - 1 May 2002
Real F X, Malats N, Lesca G, Porta M, Chopin S, Lenoir G M, Sinilnikova O
Abstract excerpt
BACKGROUND: Hereditary factors have been reported in 5-10% of cases with exocrine pancreatic cancer and recent data support a role for BRCA2. AIMS: We have studied the prevalence of germline BRCA2 mutations in two groups of patients with exocrine pancreatic cancer from an unselected series in Spain: group A included 24 cases showing familial aggregation of cancer and group B included 54 age, sex, and hospital...
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