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Article

Prevalence of BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and pancreatic cancer.

Cancer - 15 Jan 2012

Stadler Zsofia K, Salo-Mullen Erin, Patil Sujata M, Pietanza M Catherine, Vijai Joseph, Saloustros Emmanouil, Hansen Nichole A L, Kauff Noah D, Kurtz Robert C, Kelsen David P, Offit Kenneth, Robson Mark E

Abstract excerpt

BACKGROUND: Germline mutations in the BRCA2 cancer susceptibility gene are associated with an increased risk of pancreatic cancer (PC). Breast-pancreas cancer families with BRCA1 mutations have also been observed. The influence of a family history (FH) of PC on BRCA mutation prevalence in patient...

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Source

Identifiers

PMID: 21598239
DOI: 10.1002/cncr.26191

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21598239-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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