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Article

Germline BRCA Mutations in a Large Clinic-Based Cohort of Patients With Pancreatic Adenocarcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Oct 2015

Holter Spring, Borgida Ayelet, Dodd Anna, Grant Robert, Semotiuk Kara, Hedley David, Dhani Neesha, Narod Steven, Akbari Mohammad, Moore Malcolm, Gallinger Steven

Abstract excerpt

PURPOSE: The main purpose of this study was to determine the prevalence of pathogenic BRCA1 and BRCA2 mutations in a consecutively ascertained clinic-based cohort of patients with pancreatic ductal adenocarcinoma and describe the clinical and family history characteristics. PATIENTS AND METHODS: Unselected, consecutive, incident patients with pancreatic ductal adenocarcinoma were recruited at a single cancer...

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Identifiers

PMID: 25940717
DOI: 10.1200/JCO.2014.59.7401

Genes

BRCA1
BRCA2

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