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Article

The T2238C Human Atrial Natriuretic Peptide Molecular Variant and the Risk of Cardiovascular Diseases.

International journal of molecular sciences - 11 Feb 2018

Rubattu Speranza, Sciarretta Sebastiano, Marchitti Simona, Bianchi Franca, Forte Maurizio, Volpe Massimo

Abstract excerpt

Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene. The variant rs5065 (T2238C) exerts the most substantial effects. The T to C transition at the 2238 position of the gene (13-23% allele frequency in the general...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29439446
DOI: 10.3390/ijms19020540
PMCID: PMC5855762

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