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Article

Genome Reshuffling for Advanced Intercross Permutation (GRAIP): simulation and permutation for advanced intercross population analysis.

PloS one - 23 Apr 2008

Peirce Jeremy L, Broman Karl W, Lu Lu, Chesler Elissa J, Zhou Guomin, Airey David C, Birmingham Amanda E, Williams Robert W

Abstract excerpt

BACKGROUND: Advanced intercross lines (AIL) are segregating populations created using a multi-generation breeding protocol for fine mapping complex trait loci (QTL) in mice and other organisms. Applying QTL mapping methods for intercross and backcross populations, often followed by naïve permutation of individuals and phenotypes, does not account for the effect of AIL family structure in which final generations...

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PMID: 18431467
DOI: 10.1371/journal.pone.0001977
PMCID: PMC2295257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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