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Article

Transmission distortion and genetic incompatibilities between alleles in a multigenerational mouse advanced intercross line.

Genetics - 4 Jan 2022

Arends Danny, Kärst Stefan, Heise Sebastian, Korkuc Paula, Hesse Deike, Brockmann Gudrun A

Abstract excerpt

While direct additive and dominance effects on complex traits have been mapped repeatedly, additional genetic factors contributing to the heterogeneity of complex traits have been scarcely investigated. To assess genetic background effects, we investigated transmission ratio distortions (TRDs) of alleles from parent to offspring using an advanced intercross line (AIL) of an initial cross between the mouse inbred...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34791189
DOI: 10.1093/genetics/iyab192
PMCID: PMC8733443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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