Article
A simple method for combining genetic mapping data from multiple crosses and experimental designs.
PloS one - 17 Oct 2007
Peirce Jeremy L, Broman Karl W, Lu Lu, Williams Robert W
Abstract excerpt
BACKGROUND: Over the past decade many linkage studies have defined chromosomal intervals containing polymorphisms that modulate a variety of traits. Many phenotypes are now associated with enough mapping data that meta-analysis could help refine locations of known QTLs and detect many novel QTLs. METHODOLOGY/PRINCIPAL FINDINGS: We describe a simple approach to combining QTL mapping results for multiple studies...
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