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Article

A fast microelectronic array for screening and prenatal diagnosis of beta-thalassemia.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Foglieni Barbara, Galbiati Silvia, Ferrari Maurizio, Cremonesi Laura

Abstract excerpt

The electronic microchip is a recently developed technology for the fast and reliable detection of known single-nucleotide polymorphisms (SNPs) in the genome. The DNA fragment to be analyzed is directed electrophoretically into the chip, and then it is hybridized with fluorescent-tagged DNA probes specific for the mutant and wild-type sequences. The presence or absence of the mutation is detected by the...

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Identifiers

PMID: 18425480
DOI: 10.1007/978-1-59745-066-9_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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